[Answered ]-Can I use something like Hyde from within Django?

Stop creating data in your templates. Create it in your views, pass it to your templates. For example, with breadcrumbs, there is no reason whatsoever that the code to add to breadcrumb trails has to live in the template. It could live in a view, or even better, be a context processor.

One solution is to go with a Static site + services model. You use hyde to generate the static site but have your dynamic content dealt with using javascript on the client site and nice REST API on your server.