[Answer]-Django deployment with Apache on AWS — Directory Structure

Replace your wsgi.py with a WSGI hello world and take Django out of the picture.

If that works then one possibility is the third party extension modules you are using are not compatible with Python sub interpreters and are dead locking, causing the server to hang on the request and not return anything. For more details see:

• http://code.google.com/p/modwsgi/wiki/ApplicationIssues#Python_Simplified_GIL_State_API

Make sure you try that hello world WSGI application first though rather than just jump to trying the solution described in that documentation.